Amlovalsax^®-HCT

Amlovalsax^®-HCT film-coated tablets contain three substances: Amlodipine, valsartan and hydrochlorothiazide. Each of these substances helps to control high blood pressure.

• Amlodipine belongs to a group of medicines called calcium channel blockers. Amlodipine stops the influx of calcium into the wall of the blood vessels. This prevents the blood vessels from narrowing.
• Valsartan belongs to a group of medicines called angiotensin II receptor antagonists. Angiotensin II is a substance produced naturally in the body that narrows the blood vessels, thereby increasing blood pressure. Valsartan works by blocking the effect of angiotensin II.
• Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics. Hydrochlorothiazide increases the amount of urine excreted, which also reduces blood pressure.

The result of all three mechanisms is the blood vessels dilate and blood pressure is reduced.

Amlovalsax^®-HCT is used for the treatment of high blood pressure in adult patients whose blood pressure is already controlled by amlodipine, valsartan and hydrochlorothiazide and could benefit from taking all three active substances in a single film-coated tablet.