Blood clotting & circulatory disorders, thrombosis prophylaxis.
Patients who have already had a vascular occlusive disease such as myocardial infarction, stroke, or vascular surgery (e.g., bypass) are at high risk for recurrence of vascular events.1 The options for prevention and treatment have improved.2 For secondary prevention of cardiovascular disease, in addition to lifestyle interventions, there are drug treatment methods that can be individually adapted to the patient due to the possible selection from different agents, such as platelet aggregation inhibitors and anticoagulants.
Venous thromboembolism occurs in a significant proportion of patients in typical risk situations (e.g., surgery or trauma). Anticoagulant medications, particularly low-molecular-weight heparins, can reduce venous thrombosis, pulmonary embolism, and death from pulmonary embolism in these specific high-risk situations.3
1 Antithrombotic Trialists’ (ATT) Collaboration et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet, 2009, 373: 1849-1860.
2 Secondary prevention of cardiovascular disease with acetylsalicylic acid: a gap between guideline and practice. Der Arzneimittelbrief, 2013, 47: 13-14.
3 Prabinger I. et al. Guidelines for venous thromboembolism prophylaxis in Austria. Wiener Klinische Wochenschrift, 2007, 119: 739-746.